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Ye XF, Wang WY, Wang XY, Huang QF, Li Y, Wang JG

Changing the Focus: The Pernicious Anaemia Societys Work Recognising the limitations of regulatory reclassification, the Pernicious Anaemia Society (PAS) is directing their efforts into three crucial areas to dramatically improve the quality of care for patients across the UK

5-Amino-1MQ Regulatory Standing: Classified as an experimental small molecule

Statements Author contributions XH: Data curation, Formal Analysis, Writing original draft

A 2.5 mg track has short direct data and real-world support for stable maintainers, but continuing tirzepatide has much stronger evidence than stopping. At week 112, stepping down to 5 mg preserved 16.6% weight loss versus 21.9% on the top dose and 9.9% on placebo